Knowledge Hub
We're leading global efforts to predict and prevent complex diseases. Explore our publications, disease studies, webinars, thought leadership, and more.
Featured

Increasing Healthspan - Predicting & Preventing Complex Chronic Diseases
Newsletter signup
Publication
Characterizing the genetic and biological differences between endometriosis and adenomyosis
Furthering our understanding of the overlapping and unique disease mechanisms driving each condition, with direct implications for personalized diagnosis and treatment
Publication
Reproducibility of genetic risk factors identified for long COVID using combinatorial analysis
First ever confirmation of long COVID genetic associations identified in reproduction of results across US and UK patient cohorts with diverse ancestries
Publication
Increasing Healthspan - Predicting & Preventing Complex Chronic Diseases
By building a deeper understanding of disease biology we're creating a new generation of more accurate diagnostics tools and personalized and preventative medicines
Publication
Actively Protective Combinatorial Analysis: A Scalable Novel Method for Detecting Variants that Contribute to Reduced Disease Prevalence in High-risk Individuals
Learn about the discovery of a new class of disease protective targets to prevent disease in high-risk patients
Publication
New ALS disease drivers identified in genetically defined patient subgroups
First genetic evidence for targets modulated by existing therapies indicated for MND and its symptoms, such as riluzole, retigabine and baclofen
Publication
ALS Actively Protective Biology, Novel Causal Targets and Mechanistic Biomarkers
Transformational causative combinatorial analysis of ALS/MND presented at the NEALS Annual Meeting 2024
Publication
Stratifying of Alzheimer’s Disease Leads to the Identification of Actively Protective Biologies
Our mechanism-based stratification of Alzheimer’s disease patients has led to the identification of novel targets, repurposing opportunities and actively protective biology
Publication
Patient Stratification of Two Asthma Populations Reveals Distinct Genetic and Mechanistic Differences
PrecisionLife prioritized 10 of the most tractable gene targets specific to T2-low asthma in both UK Biobank and GASP asthma populations
Publication
Genetic Risk Factors for Severe and Fatigue Dominant Long COVID
PrecisionLife identified the first detailed genetic risk factors for long COVID and common mechanisms with ME/CFS and other complex diseases
Sign Up