We've generated deep insights into the biological mechanisms underpinning complex chronic diseases
We’ve discovered new biomarkers identifying clinically relevant patient subgroups who share a disease mechanism and novel drug targets or indication extension opportunities for treating them.
All these insights are stored in DiseaseBank.
DiseaseBank is our extensive repository containing the results of our disease studies, including validated SNP/gene associations, potential drug targets, tool compounds, and patient stratification groups.
These data power our specialized product pipelines for the discovery and validation of novel therapeutics, indication extension opportunities, patient stratification biomarkers, risk models and diagnostic products.
We’ve gathered detailed information on hundreds of key mechanisms and targets, including how they affect major patient subgroups across related conditions.
This has enabled us to identify novel targets and compare their influence and penetrance across multiple diseases.
DiseaseBank enables our INDx platform to systematically search for potential indication extension opportunities as well as find good tool compounds for early pharmacological target validation in new drug discovery projects.
DiseaseBank and INDx insights form the data packages necessary to support IP filings for a range of purposes.
These include method of use patents linking a drug to a new indication supported by responder biomarkers, patient stratification biomarkers as novel diagnostic tools, and proprietary risk models and clinical decision support tools.
We’ve gathered detailed information on hundreds of key mechanisms and targets, including how they affect major patient subgroups across related conditions.
This has enabled us to identify novel targets and compare their influence and penetrance across multiple diseases.
DiseaseBank enables our INDx platform to systematically search for potential indication extension opportunities as well as find good tool compounds for early pharmacological target validation in new drug discovery projects.
DiseaseBank and INDx insights form the data packages necessary to support IP filings for a range of purposes.
These include method of use patents linking a drug to a new indication supported by responder biomarkers, patient stratification biomarkers as novel diagnostic tools, and proprietary risk models and clinical decision support tools.
Using combinatorial analytics and DiseaseBank we performed high-resolution patient stratification analyses on genetic, clinical, and other ‘omics data to identify biological sub-types of endometriosis.
Our insights into the combined effects of multiple genetic variants and clinical characteristics have been used to develop predictive risk scores and clinical decision support tools for clinicians.
Our unique approach reveals many more of the biological drivers of disease than any other method
Our analysis of chronic diseases rapidly reveals insights that would usually take years of investigation
We work with collaborators worldwide and protect their most confidential and sensitive data
