Creating more personalized therapeutic opportunities from concept to clinic
Chronic diseases, such as dementia, diabetes, cardiovascular and autoimmune disorders, account for over 80% of healthcare spending.
However, they haven’t benefited from advances in genomic medicine as much as cancer or rare diseases because they are caused by a more complex interplay of multiple genes and biological factors.
People with a chronic disease may share a diagnosis, but have different causes of disease and respond to different treatments.
Multiple biological mechanisms can lead to the same clinical symptoms. Depending on which mechanism a drug targets, different treatments will be more successful in some patients than others.
The challenge for biopharma and healthcare is understanding which targets and drugs will work for which subgroups of patients.
We generate patient stratification biomarkers to deliver these precision medicine insights across dozens of chronic diseases.