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Learn how we're pioneering a new wave of precision medicine, explore our collection of publications, disease studies, webinars, thought leadership, and more

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ALS Disease Study

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Publication

Stratifying of Alzheimer’s disease leads to the identification of actively protective biologies

Our mechanism-based stratification of Alzheimer’s disease patients has led to the identification of novel targets, repurposing opportunities and actively protective biology

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Publication

Patient Stratification of Two Asthma Populations Reveals Distinct Genetic and Mechanistic Differences

PrecisionLife prioritized 10 of the most tractable gene targets specific to T2-low asthma in both UK Biobank and GASP asthma populations

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Driving Precision Medicine in CNS Disorders

Disorders of the central nervous system are a major focus for PrecisionLife.  We’ve completed analyses in more than a dozen indications and continue to add to the list as datasets become available.

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Publication

Genetic Risk Factors for Severe and Fatigue Dominant Long COVID

PrecisionLife identified the first detailed genetic risk factors for long COVID and common mechanisms with ME/CFS and other complex diseases

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Blog

Beginning to Unravel the Biological Drivers of ME

We have for the first time potentially identified some of the different genetic mechanisms causing ME/CFS and used this to stratify patients

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Blog

Genetic Subtypes in Endometriosis with Combinatorial Analytics

Latest stratification results show potential for combinatorial analytics to improve risk prediction and drive precision medicine in endometriosis

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Publication

Patient Stratification of Asthma Population Reveals Distinct Genetic & Mechanistic Differences between T2-High and T2-Low Asthma

The PrecisionLife platform identified 2,483 SNPs that were highly associated with T2-high asthma and 1,182 SNPs in the T2-low cohort with only 36 common between the two datasets.

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Publication

Genetic Risk Factors for ME/CFS Identified using Combinatorial Analysis

Groundbreaking study published in the Journal of Translational Medicine provides the first detailed genetic insights into the mechanisms underpinning ME/CFS

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Publication

Combinatorial analytics: An Essential Tool for the Delivery of Precision Medicine

An Opinion, published in the new Open Access Journal Artificial Intelligence in the Life Sciences from Elsevier, describes the need to extend our current analytical methods to effectively interrogate population data sets

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