Publication
Genetic Risk Factors for Severe and Fatigue Dominant Long COVID
PrecisionLife identified the first detailed genetic risk factors for long COVID and common mechanisms with ME/CFS and other complex diseases
Publication
Genetic Risk Factors for ME/CFS Identified using Combinatorial Analysis
Groundbreaking study published in the Journal of Translational Medicine provides the first detailed genetic insights into the mechanisms underpinning ME/CFS
Publication
Cross-Disorder Patient and Mechanistic Stratification using Combinatorial Analyses
Our analyses indicate that subgroups of patients with CNS diseases have common pathophysiological drivers that may contribute to specific common clinical manifestations.
Publication
Combinatorial Analysis of ALS and FTD Patient Genomes to Identify Cross-Disease Mechanisms
Our analyses provides insights into subgroups of patients with ALS and FTD with common pathophysiological drivers that may underlie specific overlapping clinical manifestations, allowing us to develop precision medicine interventions targeted at mechanisms occurring in both diseases.
Publication
Patient Stratification of Asthma Population Reveals Distinct Genetic & Mechanistic Differences between T2-High and T2-Low Asthma
The PrecisionLife platform identified 2,483 SNPs that were highly associated with T2-high asthma and 1,182 SNPs in the T2-low cohort with only 36 common between the two datasets.
Publication
The Era of Precision Neuroscience
DDW Neuroscience Guide - Dr Steve Gardner presents how our precision neuroscience approach is benefitting pharmaceutical companies investing in CNS
Publication
Combinatorial analytics: An Essential Tool for the Delivery of Precision Medicine
An Opinion, published in the new Open Access Journal Artificial Intelligence in the Life Sciences from Elsevier, describes the need to extend our current analytical methods to effectively interrogate population data sets
Publication
Cell Patterns: INDx Systematic Indication Extension
Paper demonstrating the potential of indication extension to systematically reposition hundreds of drugs into new indications
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