Disease Studies

Publications

See below for links to all PrecisionLife publications.


Anyone for tea? Why Alzheimer’s drug discovery might be targeting the impossible

Unique approach to precision medicine could reverse the trend in Alzheimer’s disease drug discovery and development Clinical trials in…

27/09/21
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Complexity of disease biology gives opportunities for drug discovery

Late-stage clinical trials incur the biggest costs of bringing new drugs to market. Increasingly clinical trial failures happen late….

1/09/21
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Understanding AI and its important role in MND research

“The search for new drugs to help people living with MND is long and challenging, but it is one…

22/07/21
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Precision medicine and chronic disease

Chronic diseases, which account for 85% of healthcare costs, still have significant remaining pockets of unmet medical need that…

15/07/21
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Combinatorial Analysis of Phenotypic and Clinical Risk Factors Associated With Hospitalized COVID-19 Patients

The study undertaken by PrecisionLife and Optum Labs leaders Taryn O. Hall and Kathy T.H. Zheng using data from…

8/07/21
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Combinatorial analytics: An essential tool for the delivery of precision medicine and precision agriculture

An Opinion, published in the new Open Access Journal Artificial Intelligence in the Life Sciences from Elsevier, describes the…

31/05/21
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Combinatorial analysis of phenotypic and clinical risk factors associated with hospitalized COVID-19 patients

A study using de-identified clinical claims and labs data for US COVID-19 patients. We replicated previous findings around the…

25/02/21
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The COVID-19 PHARMACOME: Rational Selection of Drug Repurposing Candidates from Multimodal Knowledge Harmonization

The SARS-CoV-2 pandemic has challenged researchers at a global scale. The scientific community’s massive response has resulted in a…

26/05/21
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AI Enabled Precision Medicine: Patient Stratification, Drug Repurposing and Combination Therapies

Access to huge patient populations with well-characterized datasets, coupled with novel analytical methods, enables the stratification of complex diseases…

26/06/20
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68 risk-associated genes identified from analysis of hospitalized COVID-19 patients

Oxford, UK – PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after…

24/06/20
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59 potential drug re-purposing candidates identified in fight against COVID-19

Oxford, UK – Using PrecisionLife’s proprietary AI enabled precision medicine platform we have identified 59 re-purposing drug candidates that…

5/05/20
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Systematic drug repurposing to enable precision medicine: A case study in breast cancer

Precision medicine and drug repurposing provide an opportunity to ameliorate the challenges of declining pharmaceutical R&D productivity, rising costs…

13/04/20
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A New Lens, European Biopharmaceutical Review

Access to huge patient datasets and improvements in analytical methods is enabling the teasing apart of complex diseases into…

1/07/19
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Delivering personalized dietary advice for health management and disease prevention

Background and Objectives: Diet plays a huge role in health, both by increasing metabolic disease risks and acutely through…

18/10/18
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Delivering precision medicine: Personalization at scale

Precision medicine promises to deliver improved patient outcomes and lower health-care costs, potentially benefiting millions of patients and saving…

3/03/17
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