Knowledge Hub
We're leading global efforts to predict and prevent complex diseases. Explore our publications, disease studies, webinars, thought leadership, and more.
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Increasing Healthspan - Predicting & Preventing Complex Chronic Diseases
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Publication
Increasing Healthspan - Predicting & Preventing Complex Chronic Diseases
By building a deeper understanding of disease biology we're creating a new generation of more accurate diagnostics tools and personalized and preventative medicines
Publication
ALS actively protective biology, novel causal targets and mechanistic biomarkers
Transformational causative combinatorial analysis of ALS/MND presented at the NEALS Annual Meeting 2024
Publication
Stratifying of Alzheimer’s disease leads to the identification of actively protective biologies
Our mechanism-based stratification of Alzheimer’s disease patients has led to the identification of novel targets, repurposing opportunities and actively protective biology
Publication
Patient Stratification of Two Asthma Populations Reveals Distinct Genetic and Mechanistic Differences
PrecisionLife prioritized 10 of the most tractable gene targets specific to T2-low asthma in both UK Biobank and GASP asthma populations
Blog
Driving Precision Medicine in CNS Disorders
Disorders of the central nervous system are a major focus for PrecisionLife. We’ve completed analyses in more than a dozen indications and continue to add to the list as datasets become available.
Publication
Genetic Risk Factors for Severe and Fatigue Dominant Long COVID
PrecisionLife identified the first detailed genetic risk factors for long COVID and common mechanisms with ME/CFS and other complex diseases
Blog
Beginning to Unravel the Biological Drivers of ME
We have for the first time potentially identified some of the different genetic mechanisms causing ME/CFS and used this to stratify patients
Blog
Genetic Subtypes in Endometriosis with Combinatorial Analytics
Latest stratification results show potential for combinatorial analytics to improve risk prediction and drive precision medicine in endometriosis
Publication
Patient Stratification of Asthma Population Reveals Distinct Genetic & Mechanistic Differences between T2-High and T2-Low Asthma
The PrecisionLife platform identified 2,483 SNPs that were highly associated with T2-high asthma and 1,182 SNPs in the T2-low cohort with only 36 common between the two datasets.
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